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Biomedical Sciences
Mailing Address:
1853 West Polk Street
Chicago, IL 60612
Contact Information:
Campus Location: Clinical Sciences North Building, Suite 300, Room 324
(312) 355-0389
https://chicago.medicine.uic.edu/education/masters-and-doctorate-programs/graduate-education-in-biomedical-sciences-gems/about
Administration:
GEMS Director: Dr. Kamal Sharma
Program Administrator: Julia Henkins
Directors of Graduate Studies: Dr. Larisa Nonn (Cancer Biology), Dr. Jalees Rehman (Cell Biology and Regenerative Medicine), Dr. Carlos Stocco (Integrative and Translational Physiology), Dr. David Ucker (Microbiology, Immunity, and Inflammation), Dr. Nava Segev (Molecular and Structural Biology), Dr. Kuei Tseng (Neurobiology)
Program Codes:
20FS6047MS (MS)
20FS6047PHD (PhD)
The GEMS Program provides PhD training to intellectually curious and diligent individuals interested in research in any area of the biomedical sciences. The program's mission is to develop skills, knowledge, and expertise during PhD education, enabling graduates to pursue biomedical research related careers.
GEMS administers the PhD in Biomedical Sciences for the UI College of Medicine. Faculty members and scientific areas of training are organized within the GEMS umbrella via six research concentrations (Cancer Biology; Cell Biology and Regenerative Medicine; Integrative and Translational Physiology; Microbiology, Immunity, and Inflammation; Molecular and Structural Biology; and Neurobiology). GEMS works with the Office of Graduate Diversity Programs and the Bridge to Doctorate Program to cultivate opportunities for diverse groups of students. The program encourages students from all backgrounds with records of exceptional achievement to apply. UIC does not discriminate on the basis of nationality, race, socioeconomic status, sex, sexual orientation, or disability.
Anatomy and Cell Biology
ANAT 403. Human Neuroanatomy. 3 hours.
Morphological organization of the nervous system. Functional correlations of neural structures. Course Information: Same as NEUS 403. Meets eight weeks of the semester. Prerequisite(s): Graduate standing and consent of the instructor. Must be in a degree program. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture.
ANAT 414. Neuroanatomy for Allied Health Program. 3 hours.
Basic Development and gross features of the central nervous system and systems neuroanatomy; motor, sensory and integrative functional areas. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture.
ANAT 439. Gross Human Anatomy I. 3 hours.
Gross structure of the adult human thorax, abdomen, pelvis and perineum, emphasizing spatial relationships and functional/clinical relevance. Includes embryology and radiology topics. Course Information: Limited to six (6) students. Prerequisite(s): Graduate standing in a degree-granting program only and consent of the instructor. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture-Discussion.
ANAT 440. Gross Human Anatomy II. 4 hours.
Gross structure of the adult human head & neck/deep back and limbs, emphasizing spatial relationships and functional/clinical relevance. Includes embryology and radiology topics. Course Information: Limited to six (6) students. Prerequisite(s): Graduate standing in a degree-granting program only and consent of the instructor. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture-Discussion.
ANAT 441. Gross Human Anatomy. 5 hours.
Functional and structural anatomy of the body. Course Information: For allied health students. Prerequisite(s): Graduate standing and consent of the instructor; or enrollment in the Doctor of Physical Therapy program or M.S. in Biomedical Visualization program. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture.
ANAT 442. Cell Structure and Human Histology. 5 hours.
Structure and function of cells and fundamental tissues. Function and microscopic anatomy of organs. Course Information: Prerequisite(s): Graduate standing and consent of the instructor. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture-Discussion.
ANAT 443. Case Studies in Clinical Anatomy. 3 hours.
Clinical approach to human anatomy by examining a series of case studies. An introduction to clinical medicine using problem based learning to integrate anatomical knowledge with clinical signs and patient symptoms. Course Information: Prerequisite(s): ANAT 441.
ANAT 511. Experimental Foundations of Psychopharmacology. 2 hours.
An introduction to the molecular mechanisms underlying synaptic transmission; review of the principal neurotransmitter systems and the biochemical, anatomical and behavioral methods used to study these systems. Course Information: Same as NEUS 511. Prerequisite(s): Grade of B or better or concurrent registration in NEUS 501 and Grade of B or better or concurrent registration in NEUS 502; or Grade of B or better or concurrent registration in BIOS 484 and Grade of B or better or concurrent registration in BIOS 485; or consent of the instructor.
ANAT 520. Concepts of Synaptic Function and Morphology. 2 hours.
Overview of current and classical methods employed in the study of synapses. A review of some of the most interesting aspects of synaptic function, such as sources of synaptic vesicles, synaptic patterns, synaptic plasticity, and synaptic specificity. Course Information: Prerequisite(s): Consent of the instructor.
ANAT 521. Plasticity in the Nervous System. 2 hours.
Neural plasticity is the ability to adaptively modify neural structure or function. Topics range from developmental plasticity to aging, including response to injury and neurodegenerative diseases, trophic factors, learning and memory, and neural transplantation. Course Information: Prerequisite(s): ANAT 403 or consent of instructor.
ANAT 523. Biology of MicroRNAs and other Small RNAs. 2 hours.
History, overview and biology of small RNA pathways, including microRNAs, siRNAs, RNA interference, roles in various biological processes, implication in disease pathophysiology, and potential therapies. Course Information: Same as BIOS 523. Prerequisite(s): Consent of the instructor.
ANAT 525. Molecular and Cellular Mechanisms of Neurodegenerative Diseases. 2 hours.
Molecular, cellular and physiological mechanisms underlying neuropathology in neurodegenerative diseases and trauma to the central and peripheral nervous system of humans. Course Information: Same as NEUS 525. Recommended background: A basic course in neuroscience.
ANAT 527. Cellular and Systems Neurobiology. 3 hours.
Molecular and cellular properties of ion channels in neurons and sensory cells and their relationship to brain and sensory systems. Course Information: Same as BIOS 527 and NEUS 527. Prerequisite(s): Credit in one neuroscience course or consent of the instructor.
ANAT 544. Advanced Craniofacial Anatomy. 3 hours.
Functional and clinical aspects of head and neck anatomy. Includes laboratory dissection and readings from the anatomical, clinical and other literature. Course Information: Same as OSCI 544. Specimen provision by sponsoring department required. Prerequisite(s): DDS or MD degrees, a course in human head and neck anatomy. Class Schedule Information: To be properly registered, students must enroll in one Laboratory-Discussion and one Lecture-Discussion.
ANAT 554. Neuroendocrinology. 2 hours.
Survey of neuroendocrine integration including neuroendocrine regulation of development, homeostasis, reproduction, and behavior. The hypothalamohypophyseal axis receives special attention from both morphologic and functional viewpoints. Course Information: Prerequisite(s): ANAT 403 or the equivalent.
ANAT 560. Practicum in the Teaching of Anatomy. 1 hour.
Provides an opportunity for supervised discussion and evaluation of materials and methods in teaching the basic anatomical sciences. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. No graduation credit. For anatomy and cell biology teaching assistants. Prerequisite(s): Consent of the instructor.
ANAT 585. Cell Biology. 4 hours.
Functional and structural organization of the cell with emphasis on the cellular basis of physiological activity. Course Information: Same as MIM 585 and PHYB 585.
ANAT 586. Cell and Molecular Neurobiology. 3 hours.
Structure and function of voltage-dependent and neurotransmitter-gated ion channels; the role of these ion channels in synaptic transmission, synaptic modification, and neuromodulation. Course Information: Same as BIOS 586. Prerequisite(s): BIOS 442 or consent of the instructor.
ANAT 594. Special Topics in Anatomy and Cell Biology. 1-4 hours.
Topics may include cell biology, molecular biology, neuronal cell biology, neuroscience, cancer biology and other topics of current significance in anatomy and cell biology. Course Information: May be repeated if topics vary. Students may register in more than one section per term. Prerequisite(s): Consent of the instructor.
ANAT 595. Department Seminar. 1 hour.
Oral presentations are made by students each session on timely journal articles, followed by in-depth discussions of the reported research. Presentation of research by invited lecturers. Course Information: Satisfactory/Unsatisfactory grading only.
ANAT 596. Independent Study. 1-4 hours.
Independent study under the direction of a faculty member.
ANAT 598. Master's Thesis Research. 0-16 hours.
Thesis research under the direction of a faculty member. Course Information: Satisfactory/Unsatisfactory grading only.
ANAT 599. Research in Anatomy. 0-16 hours.
Independent research, directed by a faculty member. Course Information: Satisfactory/Unsatisfactory grading only.
Biochemistry and Molecular Genetics
BCMG 411. Introduction to Biological Chemistry. 4 hours.
Includes chemistry of cellular constituents; enzymology; metabolism of sugars, proteins, lipids, and nucleic acids; and regulation of metabolism. Course Information: Prerequisite(s): Organic chemistry. Lecture course designed primarily for students in the College of Dentistry. Class Schedule Information: To be properly registered, students must enroll in one Conference and one Lecture.
BCMG 501. Faculty Research Seminars. 1 hour.
Faculty presentation of research areas within molecular genetics. Course Information: Satisfactory/Unsatisfactory grading only. Should be taken in the first year in the Ph.D. in Biochemistry and Molecular Genetics program. Prerequisite(s): Graduate standing in the Ph.D. in Biochemistry and Molecular Genetics program or consent of the instructor.
BCMG 502. Somatic Cell and Human Genetics. 4 hours.
The genetics of somatic cells and advanced human genetics. Gene transfer, mutagenesis, drosophila genetics, genetic linkage and human disease, cancer genetics, and gene therapy. Course Information: Prerequisite(s): GCLS 501 or consent of the instructor.
BCMG 503. Research Methods in Biochemistry and Molecular Genetics. 5 hours.
Laboratory course in experimental methods in biochemistry and molecular genetics. Course Information: May be repeated to a maximum of 10 hours. Prerequisite(s): Consent of the instructor. Open only to students entering as Ph.D. students in Biochemistry and Molecular Genetics.
BCMG 512. Experimental Design and Analysis in Molecular Genetics. 4 hours.
Methods and logic in the analysis of gene function, gene cloning, analysis of genetic changes, studies of gene expression, design of experimental controls. Course Information: Prerequisite(s): GCLS 501 or consent of the instructor.
BCMG 513. Principles of Structure Determination and Analysis. 3 hours.
Explores the relationship between structural stability, kinetic properties and function of biopolymers, with particular emphasis on proteins and nucleic acids. Course Information: Same as PMPG 513. Prerequisite(s): GCLS 501 and one year of physical chemistry, or consent of the instructor.
BCMG 514. Structure and Function of Nucleic Acids. 4 hours.
Describes the structure and function of nucleic acids. Unravels the basic molecular mechanisms underlying heredity, including replication, transcription and recombination. Course Information: Prerequisite(s): GCLS 501 or consent of the instructor.
BCMG 515. Journal Club. 1 hour.
Student presentation and critical analysis of recent journal articles and current topics in biochemistry and molecular genetics. Course Information: May be repeated. Prerequisite(s): Consent of the instructor.
BCMG 522. Strategies for Effective Scientific Communication. 1 hour.
Development of critical skills for evaluation, development, and execution of forms of scientific communication, including research and grant proposals, manuscripts describing original research, and review summaries. Course Information: Satisfactory/Unsatisfactory grading only. Prerequisite(s): Consent of the instructor.
BCMG 526. Molecular and Genetic Analysis of Development. 3 hours.
Examines developmental mechanisms used in animal model systems. Course Information: Same as BIOS 526. Prerequisite(s): Graduate standing or consent of the instructor.
BCMG 531. Medical Biochemistry and Nutrition. 3 hours.
Chemistry of Biopolymers; enzymology; metabolism of carbohydrates, Lipids, amino acids and proteins; molecular biology. Course Information: Intended for first year medical students. Prerequisite(s): Membership in the College of Medicine (COM) M1 medical school class. Intended/available only for first year medical students registered in the COM.
BCMG 533. Nutrition for Medical Students. 2 hours.
Biochemical and nutritional basis of disease including heart disease, hypertension, obesity, malnutrition, and cancer. Course Information: Prerequisite(s): BCMG 531 and BCMG 532 and membership in the medical school or consent of the instructor. Intended primarily for medical students.
BCMG 561. Biochemistry of Cellular Regulation. 3 hours.
Membrane structure and function, transport, receptor and signal transduction mechanisms and growth factors. Cytoskeleton and motility, cell-cell communication, enzyme cascades and cellular control mechanisms.
BCMG 563. Principles of Molecular Medicine. 3 hours.
A lecture/discussion/writing course which integrates biochemical and molecular biological concepts into a clinical context. Diseases will be described in terms of molecular mechanisms. Course Information: Prerequisite(s): Consent of the instructor.
BCMG 575. Topics in Biochemistry and Molecular Genetics. 3 hours.
Students will be exposed to, present , and discuss recent scientific literature in biochemistry and molecular genetics. Course Information: May be repeated. Prerequisite(s): Completion of the first year of the program and consent of the instructor. Class Schedule Information: To be properly registered, students must enroll in one Discussion and one Lecture.
BCMG 594. Special Topics in Biochemistry and Molecular Genetics. 1-3 hours.
Topics of current interest in the field of biochemistry and molecular genetics, and may include protein structure, membrane proteins and trafficking, development and gene regulation, signal transduction, and cancer biology. Course Information: May be repeated to a maximum of 6 hours. Students may register in more than one section per term. Prerequisite(s): Consent of the instructor.
BCMG 595. Student Research Seminars. 1 hour.
Research presentations by graduate students in the biochemistry and molecular genetics program. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Prerequisite(s): Consent of the instructor.
BCMG 598. Masters Thesis Research. 0-16 hours.
Investigation carried out by M.S. candidate under the direction of a faculty member leading to the M.S. in Biochemistry and Molecular Genetics. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Prerequisite(s): Consent of the instructor.
BCMG 599. Ph.D. Thesis Research. 0-16 hours.
Independent dissertation research by the student, under the guidance of the adviser. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Prerequisite(s): Advanced standing in the Ph.D. in Biochemistry and Molecular Genetics program.
Microbiology and Immunology
MIM 551. Advanced Immunology. 2 hours.
Concepts in immunochemistry, immunogenetics, molecular immunology, cellular immunology and immunopathology at the intermediate level. Course Information: Prerequisite(s): GCLS 501, GCLS 502, GCLS 503 and GCLS 510 or consent of the instructor.
MIM 553. Molecular Biology of Viruses. 2 hours.
Animal viruses including basic structure and viral nucleic acids; emphasizes molecular organization of viral genomes; cellular and molecular events during virus replication and viral transformation. Course Information: Prerequisite(s): GCLS 501, GCLS 502, GCLS 503, and GCLS 511 or consent of the instructor.
MIM 554. Molecular Aspects of Microbiology. 3 hours.
Basic concepts of prokaryotic and eukaryotic genetics; gene structure and function; gene expression; molecular aspects of mutation and recombination; chromosome structure and function. Course Information: Prerequisite(s): BCHE 460.
MIM 560. Microbial Pathogenesis. 2 hours.
Genetics, molecular biology and physiology of pathogenic bacteria, and host-pathogen interactions. Course Information: Credit is not given for MIM 560 if the student has credit for MIM 552. Prerequisite(s): GCLS 501, GCLS 502, GCLS 503, and GCLS 511 or consent of the instructor.
MIM 585. Cell Biology. 4 hours.
Functional and structural organization of the cell with emphasis on the cellular basis of physiological activity. Course Information: Same as ANAT 585 and PHYB 585.
MIM 594. Special Topics in Microbiology, Immunology and Virology. 1-2 hours.
Advanced topics are covered in depth. Topics vary yearly. Course Information: Prerequisite(s): BCHE 460 and MIM 451 and MIM 455 and MIM 552 and MIM 553 and consent of the instructor.
MIM 595. Seminar in Microbiology and Immunology. 1 hour.
Topics of current research interest are presented by guest lecturers from outside institutions in areas of molecular biology, bacteriology, virology and immunology. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Presentation must be understandable to the broad Microbiology community in addition to the specialist.
MIM 598. Research in Molecular Biology and Immunology. 0-16 hours.
M.S. thesis research on problems in microbiology, immunology, virology and molecular biology. Course Information: Satisfactory/Unsatisfactory grading only. Prerequisite(s): Graduate standing in microbiology and immunology.
MIM 599. Research in Molecular Biology and Immunology. 0-16 hours.
Ph.D. thesis research on problems in microbiology, immunology, virology and molecular biology. Course Information: Satisfactory/Unsatisfactory grading only. Prerequisite(s): Graduate standing in microbiology and immunology.
Pathology
PATH 421. General Pathology - Dental. 3 hours.
Basic principles of pathological processes. Course Information: Prerequisite(s): ANAT 440 and PATH 407 and PHYB 401; or consent of instructor. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture.
PATH 422. Systemic Pathology - Dentistry. 3 hours.
Disease process affecting specific organs. Course Information: Prerequisite(s): PATH 421. Class Schedule Information: To be properly registered, students must enroll in one Laboratory and one Lecture.
PATH 507. Physiological Basis of Pathology. 2 hours.
Subject matter allied to general pathology but going deeper into physical chemistry and physiological principles, as set forth in N.R. Joseph's "Comparative Physical Biology." Course Information: Same as HSTL 507. Prerequisite(s): HSTL 401; or PATH 421 and PATH 422.
PATH 510. General Pathology. 3 hours.
Introduction to the science of disease for graduate students in areas of biomedical research with a focus on the mechanisms of basic pathological processes at the molecular, cellular, tissue, and whole organism levels. Course Information: Prerequisite(s): Consent of the instructor. Recommended background: Basic molecular and cell biology is highly recommended.
PATH 511. Pathobiology of Cancer. 3 hours.
Introduction to principles of carcinogenesis, tumor biology, and oncology, including cancer epidemiology, molecular-cellular basis of cancer, tumor progression, invasion and metastasis, and prevention, detection, diagnosis, and therapy of cancer. Course Information: Same as GEMS 512. Prerequisite(s): Consent of the instructor. Recommended background: Basic knowledge of molecular and cell biology is highly recommended.
PATH 512. Molecular Epidemiology and Biomarkers of Disease. 3 hours.
Major theoretical concepts and practical issues involved in research involving molecular biomarkers in human populations, emphasizing examples from the cancer research literature. Course Information: Same as EPID 512. Prerequisite(s): Consent of the instructor. Recommended background: Some biology or medical background is recommended for epidemiology students taking this course.
PATH 513. Special Topics in Pathology. 1-4 hours.
Topics of current interest in the fields of experimental pathology, cancer biology, molecular epidemiology, experimental design and analysis, biomarker research, and cancer prevention. Course Information: May be repeated. Prerequisite(s): Approval of the department.
PATH 595. Pathology Seminar and Journal Club. 2 hours.
Weekly seminar and journal club covering selected fields of interest and research in pathology. Course Information: Satisfactory/Unsatisfactory grading only. Class Schedule Information: To be properly registered, students must enroll in one Conference and one Lecture-Discussion.
PATH 598. Master's Thesis Research. 0-16 hours.
Research in experimental pathology towards M.S. degree. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Students may register in more than one section per term.
PATH 599. Ph.D. Thesis Research. 0-16 hours.
Research in experimental pathology towards a Ph.D. degree. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Students may register in more than one section per term.
Pharmacology
PCOL 430. Principles of Toxicology. 2 hours.
Examines the toxic effects of drugs and chemicals on organ systems. Lectures emphasize basic principles, effects on specific organ systems, major classes of toxic chemicals, and specialized topics such as forensic and industrial toxicology. Course Information: Same as BPS 430. Credit is not given for PCOL 430 if the student has credit for EOHS 457.
PCOL 510. Molecular Pharmacology of Platelets, Thrombosis and Vascular System. 2 hours.
Molecular mechanism and therapeutic approaches to: platelet functions, thrombosis, hemostasis, and vascular biology. The platelet as a model cell for molecular mechanisms of intracellular signal transduction and cell adhesion. Course Information: Prerequisite(s): Credit or concurrent registration in GCLS 501 and GCLS 503; or consent of the instructor.
PCOL 530. Pharmacology and Biology of the Vessel Wall. 2 hours.
Regulation of physiological and pathological processes in the cardiovascular system; e.g. endothelial barrier, cell adhesion, smooth muscle proliferation, angiogenesis, endothelial gene expression. Pharmacological treatment of cardiovascular diseases. Course Information: Prerequisite(s): Credit or concurrent registration in GCLS 501 and GCLS 503; and consent of the instructor.
PCOL 540. Ion Channels: Structure, Function, Pharmacology and Pathology. 2 hours.
The concept of ion channels is treated from the perspectives of their molecular structures and functions. Modulation, pathological conditions (channelopathies), and pharmacological intervention will also be treated. Course Information: Same as PHYB 540. Recommended background: One undergraduate course in Biochemistry and one in Physiology, or consent of the instructor.
PCOL 550. The Biology and Pharmacology of the Lung. 2 hours.
Covers topics in lung biology and physiology. The importance of impaired lung function in inducing lung diseases and potential therapeutics will be discussed. Course Information: Prerequisite(s): Credit or concurrent registration in GCLS 501; and Credit or concurrent registration in GCLS 503; or consent of the instructor.
PCOL 560. Graduate Pharmacology. 3 hours.
General principles of molecular mechanisms of drug action in selected areas of pharmacology such as factors altering pharmacokinetics and pharmacodynamics. Mechanisms of cardiovascular and pulmonary disease and cancer will be focused. Course Information: Recommended background: GCLS 501 and GCLS 502 and GCLS 503. Class Schedule Information: To be properly registered, students must enroll in one Lecture-Discussion and one Discussion.
PCOL 594. Special Topics. 1 hour.
Organized presentation and discussion of rapidly developing research areas in molecular, cellular and systems pharmacology. Course Information: May be repeated. Prerequisite(s): Consent of the instructor.
PCOL 595. Pharmacology Seminar. 1 hour.
Presentation of research and/or current literature by invited lecturers and students. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated.
PCOL 598. M.S. Thesis Research. 0-16 hours.
Thesis work under the supervision of a graduate advisor. Course Information: Satisfactory/Unsatisfactory grading only.
PCOL 599. Ph.D. Thesis Research. 0-16 hours.
Thesis work under the supervision of a graduate advisor. Course Information: Satisfactory/Unsatisfactory grading only.
Physiology and Biophysics
PHYB 502. Physiology of Reproduction. 2 hours.
The purpose of this course is to enable students to acquire a detailed and up-to-date understanding of the Biology of Reproduction at both the physiological and molecular levels.
PHYB 512. Gastrointestinal Physiology. 2 hours.
Advanced study of the physiology of the gastrointestinal tract. Special emphasis will be placed on recent developments in cellular and molecular aspects and on how they relate to established concepts in the literature. Course Information: Prerequisite(s): PHYB 402 or consent of the instructor.
PHYB 516. Physiology and Biochemistry of Muscle Contraction. 2 hours.
Structure and function of myosin, actin, tropomyosin, troponin, and the sarcoplasmic reticulum; control, energetics, and mechanism of muscle contraction; gene expression.
PHYB 518. Cardiovascular Pathophysiology. 3 hours.
Focuses on pathogenesis and fundamental mechanisms of impaired cardiac performance due to systemic and cardiac disease. Function and pathology of diseased heart in relation to normal healthy states and therapeutic interventions. Course Information: Prerequisite(s): GCLS 500 and either GCLS 501 or GCLS 502 or GCLS 503; or consent of the course coordinator.
PHYB 523. Tissue Inflammation and Repair. 3 hours.
Mechanisms of tissue inflammation and repair in various tissues and different pathological conditions. This course will focus on current research related to factors influencing inflammation and tissue repair including the effects of exercise. Course Information: Same as KN 523. Prerequisite(s): Graduate standing; and consent of the instructor.
PHYB 530. Stem Cells. 2 hours.
Discussion of stem cell development into different cell types that may offer a renewable source of replacement cells to treat diseases, conditions, and disabilities. Cells from adult tissue, fetal tissue, and embryonic sources are discussed. Course Information: Recommended background: Knowledge of cell biology.
PHYB 540. Ion Channels: Structure, Function, Pharmacology and Pathology. 2 hours.
The concept of ion channels is treated from the perspectives of their molecular structures and functions. Modulation, pathological conditions (channelopathies), and pharmacological intervention will also be treated. Course Information: Same as PCOL 540. Recommended background: One undergraduate course in biochemistry and one in physiology, or consent of the instructor.
PHYB 551. Human Physiology I. 5 hours.
Lectures and conferences in human physiology. Emphasis is on cellular, nerve-muscle, cardiovascular, respiratory and renal physiology. Course Information: Prerequisite(s): Mathematics, undergraduate physics, and organic chemistry; or consent of instructor. Recommended background: Course work in biological sciences. Class Schedule Information: To be properly registered, students must enroll in one Conference and one Lecture.
PHYB 552. Human Physiology II. 5 hours.
Lectures and conferences in human physiology. Continuation of PHYB 551 Human Physiology II. Emphasis is on central nervous, endocrine and reproductive systems physiology. Course Information: Prerequisite(s): PHYB 551. Recommended background: Course work in biological sciences.
PHYB 569. Methods in Experimental Physiology. 3 hours.
Primarily for students in physiology. Registration limited to eight. A laboratory course designed to acquaint students with advanced techniques and methodology in physiologic investigations. Course Information: Prerequisite(s): Enrollment in the M.S. or Ph.D. in Physiology and Biophysics program, and credit or concurrent registration in PHYB 401 or the equivalent; or consent of the instructor.
PHYB 571. Clinical Applications of Physiology I. 2 hours.
Students in this course will apply principles of basic physiology to select topics in state of the art science affecting both clinical issues and research designed to address these issues. Course Information:.
PHYB 572. Clinical Applications of Physiology II. 2 hours.
Students in this course will apply principles of basic physiology to select topics in state of the art science affecting both clinical issues and research designed to address these issues. Course Information: Prerequisite(s): Mathematics, undergraduate physics, and organic chemistry; or consent of instructor. Recommended background: Extensive course work in undergraduate sciences, particularly biological sciences. Corequisites: Requires concurrent registration in PHYB 552.
PHYB 585. Cell Biology. 4 hours.
Functional and structural organization of the cell with emphasis on the cellular basis of physiological activity. Course Information: Same as ANAT 585 and MIM 585.
PHYB 586. Cell Physiology. 3 hours.
Advanced functional and structural organization of the cell with emphasis on the cellular basis of physiological activity. Course Information: Prerequisite(s): PHYB 552 and GCLS 501 and GCLS 503; or consent of the instructor.
PHYB 590. Seminar in Cardiovascular Science. 1 hour.
Weekly seminars on advanced cardiovascular science topics by staff and invited speakers. Course Information: Satisfactory/Unsatisactory grading only. Prerequisite(s): Consent from the course coordinator. Enrollment is open to students following completion of their first year of graduate studies.
PHYB 591. Departmental Seminar. 1 hour.
Weekly seminar by staff and invited speakers. Course Information: Satisfactory/Unsatisfactory grading only. May be repeated. Required of all physiology and biophysics students each fall and spring semester while enrolled in the graduate program. Prerequisite(s): Graduate or professional standing.
PHYB 592. Experimental and Diagnostic Methods in Cardiovascular Science. 3 hours.
Establishes the fundamental physical basis between diagnostic and experimental procedures in the clinic and basic science laboratory, combined with some direct observation of methods used for experimental approaches. Course Information: Prerequisite(s): GCLS 500 and either GCLS 501 or GCLS 502 or GCLS 503; or consent of the course coordinator.
PHYB 594. Special Topics in Physiology and Biophysics. 1-4 hours.
Topics may include bioengineering, endocrinology, membrane biology, ion transport and its regulation, muscle physiology, neurophysiology, molecular neurobiology and others of current significance in physiology and biophysics. Course Information: May be repeated. Students may register in more than one section per term. Prerequisite(s): Consent of the instructor.
PHYB 595. Journal Club and Seminar in Physiology. 1 hour.
Student presentation and discussion of assigned topics of current importance in physiology and biophysics as well as related fields. Course Information: Satisfactory/Unsatisfactory grading only. Prerequisite(s): Consent of the instructor. Limited to degree candidates in physiology and biophysics.
PHYB 596. Independent Study. 1-4 hours.
Individual study guided by a faculty member. The format of the course, examination and grading to be established by the faculty member. Course Information: May be repeated. Students may register in more than one section per term. Prerequisite(s): Consent of the instructor.
PHYB 598. M.S. Thesis Research. 0-16 hours.
Thesis work under the supervision of a graduate adviser. Course Information: Satisfactory/Unsatisfactory grading only. Prerequisite(s): Graduate standing in physiology and biophysics.
PHYB 599. Ph.D. Thesis Research. 0-16 hours.
Thesis work under the supervision of a graduate adviser. Course Information: Satisfactory/Unsatisfactory grading only.